Volume 2 is a cover for Noé. Similarly to Vanitas, at the top of Noé’s frame are lilies, which symbolize purity. Noé also has a book and quill, which is a reference to the book and quill that he’s been using to write the story. The frame is an oval made of skeletal spines, and this shows up on a lot of covers as a vanitas symbol for death.
The frame itself is in a sunburst shape that resembles a monstrance. A monstrance is a vessel designed to display an object, usually the Eucharist or a relic of a saint. Interpreting this rather broadly, maybe this is what Noé is doing for Vanitas’s life. By writing a case study for Vanitas, he’s displaying this person’s life in this way. (As an aside, the Eucharist is the drink of life, Christ’s blood, and vampires drink blood to live in folklore.)
The contents of the frame are of Teacher reaching out between curtains, with his arms gesturing past Noé’s head, as if he’s encouraging Noé to go forward. There are stars in the background and on Teacher himself. The curtains are purple (Noé’s color) while Teacher is blue.
Stars in this story are often associated with vampires, and other celestial objects have proven meaningful as well. All vampires in the story so far are vampires of the Red Moon, except in the case of the vampire Vanitas, who is of the Blue Moon and for that reason is despised. The meta angle to this may be to keep the connection of vampires being creatures of the night.
The way the curtains are being pulled away is reminiscent of the beginning of a play at a theater. A story for Noé is starting here, and given how Teacher wanted to observe what Louis would do as a cursebearer, Teacher is probably doing the same with Noé. He is an audience member to the tale that Noé is a part of, and for all we know he is the one making this particular tale happen.